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A group of drugs that competitively block histamine receptors in the body, which leads to inhibition of the effects mediated by them.
Histamine is a neurotransmitter that can affect the respiratory tract (causing swelling of the nasal mucosa, bronchospasm), skin (itching, blistering-hyperemic reaction), gastrointestinal tract (intestinal colic, stimulation of gastric secretion), cardiovascular system (expansion of capillary vessels, increased vascular permeability, hypotension, heart rhythm disturbances), smooth muscles.
An increase in its effect causes allergic reactions, therefore antihistamines are used to combat the manifestations of allergies. Another area of their application is symptomatic therapy / elimination of symptoms for colds.
Currently, there are three groups of drugs (according to the receptors they block):
H1 blockers - used in the treatment of allergic diseases.
H2 blockers - used in the treatment of stomach diseases (help to reduce gastric secretion).
H3 blockers - used in the treatment of neurological diseases.
There are currently three generations of allergy medications. The 1st generation allergy pills were developed in 1936 and are still in use today. Second- and third-generation tablets have several advantages over first-order drugs
Allergy tablets are designed to eliminate specific negative symptoms that result from a reaction to a specific allergen. Many substances can act as irritants:
pollen of plants;
food products;
cosmetics;
household chemicals;
dust;
pet hair;
etc.
Allergy medications significantly alleviate the condition of people diagnosed with this pathology, improving their quality of life and allowing them to remain efficient.
Allergy in medicine is usually called the response of the human immune system to any irritating factor (allergen). Contact with an irritant and / or with many irritants leads to an active state of a biologically active component - histamine (an allergy mediator found in most body tissues). This biologically active substance is not dangerous to the body if its activity is not observed. In the active state, histamine leads to dysfunction of organs and systems - nervous, muscular, respiratory, digestive, etc.
As a result, the following symptoms may be observed:
Lachrymation, profuse discharge from the sinuses.
Violation of nasal breathing.
Sneezing, coughing.
Bronchospasm / respiratory distress.
Activation of the process of secretion of gastric juice.
Violation of the digestive process and stool (diarrhea).
Dilation of blood vessels.
Swelling.
Skin rashes.
Headaches, dizziness, fainting.
Muscle spasms.
Blood pressure surges.
Arrhythmia.
Dry mouth, voice changes.
Chest / heart pain and more.